Human exosomes
Exosomes are endosomal-derived vesicles containing complex nucleic acids, proteins, lipids, and metabolites. They play a key role in cell-to-cell communication and signal transduction and aresecreted in various biological fluids including cerebrospinal fluid, saliva, ascites, urine, and serum amongst others. Exosomes are small (approximately 40-160 nm in diameter, 100 nm on average) with a distinctive bilipid protein structure. They can carry and exchange a variety of cargos between cells and are used as non-invasive biomarkers for several diseases. Due to their unique characteristics, exosomes are considered the best biomarkers for cancer diagnosis. Exosomes derived from various sources have been used in research related to the prognosis and diagnosis of a variety of diseases including cardiovascular and degenerative diseases, arthritis, diabetes mellitus, neurological diseases as well as cancers.
We at Memel Biotech are offering the following R&D grade types of exosomes:
| Product name | Product type |
|---|---|
| TE-001 | Adipocyte-derived MSC exosomes |
| TE-002 | Bone marrow-derived MSC exosomes |
| TE-003 | Cord blood-derived MSC exosomes |
| TE-004 | PBMC-derived NK exosomes |
| TE-005 | Any cancer cell line exosomes (Customized) |
| Specification | |
|---|---|
| Cell origin species | Human |
| Particle number | ≥1×10^9/ml |
| Size distribution | 50-200 nm range (Average: 100 nm) |
| Fill volume | 0.5 ml |
| Diluent | Dissolved in PBS (liquid type) |
| Product format | Frozen |
| Isolation | TFF based |
| Marker expression | Positive for CD63 and HSP70, Negative for Calnexin |
| Stability | 6 month-1 year (-80 °C) |
| Mycoplasma | None detected |
| Storage condition | (-80 °C) |
Are you seeking a partner for exosome research and development? At Memel Biotech, we offer comprehensive support, from initial setup to scaling and commercialization, ensuring the most suitable solutions for your needs.